PROPHYLACTIC LIGNOCAINE AND EARLY POST-CORONARY ARTERY OCCLUSION DYSRHYTHMIAS IN ANAESTHETIZED GREYHOUNDS
نویسندگان
چکیده
منابع مشابه
Coronary Artery Disease and Dysrhythmias
CAD is a generic designation for many different conditions that involve obstructed blood flow through the coronary arteries. The most prevalent etiologies of CAD are atherosclerosis, coronary vasospasm, and microvascular angina. Microvascular angina results from poor function of the smaller blood vessels that supply the heart. Atherosclerosis is by far the most common cause of CAD and is the fo...
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1 The antidysrhythmic, haemodynamic and metabolic effects of a new prospective antianginal and antidysrhythmic agent, N-(3-3-dipenylpropyl)-alpha-methyl-beta-cyclohexylethylamine hydrochloride (MG 8926), have been compared with the chemically related substance, prenylamine, in anaesthetized greyhounds and guinea-pigs. 2 When given intravenously 20 min beforehand, both MG 8926 and prenylamine (5...
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Specific rabbit anti-cardiolipin (anti-CL) antibodies were used to investigate the hypothesis that cardiolipin, associated with mitochondrial membrane proteins, binds Cl and facilitates activation of the complement cascade following reperfusion of ischemic myocardium. By immunoelectron microscopy, anti-CL localized to subsarcolemmal mitochondria, emerging through breaks in membranes of damaged ...
متن کاملCoronary Artery Occlusion
We evaluated the effect of altered loading conditions on left ventricular (LV) diastolic pressurevolume relations during acute coronary artery occlusion that was produced by inflation of an intracoronary balloon. Open-chest anesthetized dogs (n=18) were instrumented so that LV pressure (micromanometer) and LV volume (conductance) could be measured without disturbing the pericardium. The effects...
متن کاملCoronary Artery Occlusion
coronary artery was occluded for 15-min periods in closed-chest conscious dogs by inflating a balloon cuff previously implanted around the artery. The degree of myocardial ischemia was estimated by summating the S-T elevation recorded from 12 myocardial electrodes. Heart rate was increased by atropine or pacing and decreased by electrical stimulation of the vagus nerve. Hypotension was produced...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 1980
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.1980.tb10978.x